Advanced glycoxidation and lipoxidation end products (AGEs and ALEs): an overview of their mechanisms of formation
نویسندگان
چکیده
منابع مشابه
Diabetes and advanced glycoxidation end products.
The morbidity caused by diabetes has traditionally been classified into macroand microvascular complications. Although macrovascular complications have received greater attention, microvascular complications are unique to diabetes, and hyperglycemia contributes to their development. Numerous hyperglycemia-related mechanisms are hypothesized to mediate microand macrovascular complications. These...
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چکیده ندارد.
15 صفحه اولProinflammatory effects of advanced lipoxidation end products in monocytes.
OBJECTIVE The reactions of carbohydrate- or lipid-derived intermediates with proteins lead to the formation of Maillard reaction products, which subsequently leads to the formation of advanced glycation/lipoxidation end products (AGE/ALEs). Levels of AGE/ALEs are increased in diseases like diabetes. Unlike AGEs, very little is known about ALE effects in vitro. We hypothesized that ALEs can have...
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ژورنال
عنوان ژورنال: Free Radical Research
سال: 2013
ISSN: 1071-5762,1029-2470
DOI: 10.3109/10715762.2013.815348